One way to backup the registry is to create a System Restore snapshot. System Restore returns your computer to a previous snapshot without losing recent personal information, such as documents, history lists, favorites, or e-mail. It monitors the computer and many applications for changes and creates restore points. You restore these snapshots when your configuration isn't working. This method is unreliable in case you want to rollback the registry changes made a longtime ago, in which case the System Restore might have purged that particular restore point - due to space constraints or due to a recent system restore point or even a Restore point corruption. Please remember, System Restore points get deleted for many reasons, making it unreliable, especially in the long run.
For more help, see : Creating a System Restore point and Using System Restore to Undo Changes if Problems Occur